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What are the changes in the body that causes Lipofibroma?
(Speciality: Doctor)
Lipoma is benign (non-cancerous), slow growing painless tumor composed of fatty tissue. Lipomas are soft to the touch, usually movable, and are generally painless. Lipomas are commonly found in adults from 40 to 60 years of age, but can also be found in children. The exact etiology of lipomas remains uncertain, an association with gene rearrangements of chromosome 12 has been established in cases of solitary lipomas, The tendency to develop a lipoma is not necessarily hereditary although hereditary conditions, such as familial multiple lipomatosis, may include lipoma development. Cases have been reported where minor injuries are alleged to have triggered the growth of a lipoma, called "post-traumatic lipomas. The link between the trauma and lipoma formation is controversial. Presentation will according to site it is present. Lipomas are rarely life-threatening and the common subcutaneous lipomas are not a serious condition. Lipomas growing in internal organs can be more dangerous, for example lipomas in the gastrointestinal tract can cause bleeding, ulceration and painful obstructions. Malignant transformation of lipomas into liposarcomas is very rare and most liposarcomas are not produced from pre-existing benign lesions, although a few cases of malignant transformation have been described for bone and kidney lipomas. It is possible these few reported cases were well-differentiated liposarcomas in which the subtle malignant characteristics were missed when the tumour was first examined Deep lipomas have a greater tendency to recur than superficial lipomas, because complete surgical removal of deep lipomas is not always possible.

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